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TitleStructure of Thermus thermophilus homoisocitrate dehydrogenase in complex with a designed inhibitor
Journal, issue, pagesJ. Biochem., Vol. 150, Page 607-614, Year 2011
Publish dateDec 13, 2010 (structure data deposition date)
AuthorsNango, E. / Yamamoto, T. / Kumasaka, T. / Eguchi, T.
External linksJ. Biochem. / PubMed:21813504
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-3asj:
Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-XYN:
3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-XYM:
(2Z)-3-[(carboxymethyl)sulfanyl]-2-hydroxyprop-2-enoic acid

ChemComp-HOH:
WATER

Source
  • thermus thermophilus (bacteria)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / BETA-HYDROXY ACID OXIDATIVE DECARBOXYLASE / LYSINE BIOSYNTHESIS / OXIDOREDUCTASE / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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