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Structure paper

TitleProduct-assisted catalysis as the basis of the reaction specificity of threonine synthase.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 2774-2784, Year 2011
Publish dateFeb 13, 2010 (structure data deposition date)
AuthorsMurakawa, T. / Machida, Y. / Hayashi, H.
External linksJ. Biol. Chem. / PubMed:21084312
MethodsX-ray diffraction
Resolution1.92 - 2.1 Å
Structure data

PDB-3aex:
Catalytic intermediate analogue of threonine synthase from Thermus thermophilus HB8
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3aey:
Apo form of threonine synthase from Thermus thermophilus HB8
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

Chemicals

ChemComp-AN7:
(3E)-4-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}-2-oxobut-3-enoic acid

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • thermus thermophilus (bacteria)
KeywordsLYASE / Threonine synthase / PLP / Pyridoxal phosphate

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