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Structure paper

TitleStructural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 444-452, Year 2010
Publish dateSep 9, 2009 (structure data deposition date)
AuthorsNakamura, T. / Meshitsuka, S. / Kitagawa, S. / Abe, N. / Yamada, J. / Ishino, T. / Nakano, H. / Tsuzuki, T. / Doi, T. / Kobayashi, Y. ...Nakamura, T. / Meshitsuka, S. / Kitagawa, S. / Abe, N. / Yamada, J. / Ishino, T. / Nakano, H. / Tsuzuki, T. / Doi, T. / Kobayashi, Y. / Fujii, S. / Sekiguchi, M. / Yamagata, Y.
External linksJ. Biol. Chem. / PubMed:19864691
MethodsX-ray diffraction
Resolution1.8 - 2.56 Å
Structure data

PDB-3a6s:
Crystal structure of the MutT protein
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3a6t:
Crystal structure of MutT-8-OXO-DGMP complex
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-3a6u:
Crystal structure of MutT-8-OXO-dGMP-MN(II) complex
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-3a6v:
Crystal structure of the MutT protein in MN(II) bound holo form
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-8OG:
8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE

ChemComp-MN:
Unknown entry

Source
  • escherichia coli k-12 (bacteria)
KeywordsHYDROLASE / ALPHA-BETA-ALPHA SANDWICH / DNA DAMAGE / DNA REPAIR / DNA REPLICATION / MUTATOR PROTEIN / ENZYME-PRODUCT-METAL COMPLEX

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