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TitleBinding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
Journal, issue, pagesNucleic Acids Res., Vol. 26, Page 3001-3005, Year 1998
Publish dateFeb 18, 1998 (structure data deposition date)
AuthorsDutta, R. / Gao, Y.G. / Priebe, W. / Wang, A.H.
External linksNucleic Acids Res. / PubMed:9611247
MethodsX-ray diffraction
Resolution2 - 2.1 Å
Structure data

PDB-380d:
BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-381d:
BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-DM8:
2'-BROMO-4'-EPIDAUNORUBICIN

ChemComp-HOH:
WATER

KeywordsDNA / RIGHT HANDED DNA / DOUBLE HELIX / MODIFIED / COMPLEXED WITH DRUG / MISMATCHED

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