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TitleIn vitro and in vivo activity of OSUAB-0284, a preclinical candidate for Staphylococcus aureus infection
Journal, issue, pagesTo Be Published
Publish dateJul 1, 2026 (structure data deposition date)
AuthorsMann CA / West JC / Cassel SR / Wheat CT / Landgraf AD / Tomkovicz JV / Zhao X / Eaton S / Dellos-Nolan S / Baldridge I ...Mann CA / West JC / Cassel SR / Wheat CT / Landgraf AD / Tomkovicz JV / Zhao X / Eaton S / Dellos-Nolan S / Baldridge I / Srivastava P / Kennedy-Mendez A / Pillar CM / Hufnagel DA / Kebriaei R / Bell CE / Wozniak DJ / Yalowich JC / Mitton-Fry MJ
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.75 Å
Structure data

77872

36up

EMDB-77872, PDB-36up:
S. aureus DNA Gyrase in complex with OSUAB-0284 and DNA
Method: EM (single particle) / Resolution: 2.75 Å

Chemicals

PDB-1dl2:
CRYSTAL STRUCTURE OF CLASS I ALPHA-1,2-MANNOSIDASE FROM SACCHAROMYCES CEREVISIAE AT 1.54 ANGSTROM RESOLUTION

ChemComp-MN:
Unknown entry

Source
  • staphylococcus aureus subsp. aureus n315 (bacteria)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA / Topoisomerase / NBTI / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex

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