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Structure paper

TitleStructural basis for antibody catalysis of a disfavored ring closure reaction.
Journal, issue, pagesBiochemistry, Vol. 38, Page 7062-7074, Year 1999
Publish dateMar 18, 1998 (structure data deposition date)
AuthorsGruber, K. / Zhou, B. / Houk, K.N. / Lerner, R.A. / Shevlin, C.G. / Wilson, I.A.
External linksBiochemistry / PubMed:10353817
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-25c8:
CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-35c8:
CATALYTIC ANTIBODY 5C8, FAB-INHIBITOR COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GEP:
N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION

ChemComp-HOH:
WATER

ChemComp-NOX:
N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE

Source
  • mus musculus (house mouse)
KeywordsCATALYTIC ANTIBODY / FAB / RING CLOSURE REACTION

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