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-Structure paper
Title | Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 19, Page 1753-1757, Year 2009 |
Publish date | Feb 22, 2008 (structure data deposition date) |
![]() | Asoh, K. / Kohchi, M. / Hyoudoh, I. / Ohtsuka, T. / Masubuchi, M. / Kawasaki, K. / Ebiike, H. / Shiratori, Y. / Fukami, T.A. / Kondoh, O. ...Asoh, K. / Kohchi, M. / Hyoudoh, I. / Ohtsuka, T. / Masubuchi, M. / Kawasaki, K. / Ebiike, H. / Shiratori, Y. / Fukami, T.A. / Kondoh, O. / Tsukaguchi, T. / Ishii, N. / Aoki, Y. / Shimma, N. / Sakaitani, M. |
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Methods | X-ray diffraction |
Resolution | 2.4 - 2.6 Å |
Structure data | ![]() PDB-2zir: ![]() PDB-2zis: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-ZN: ![]() ChemComp-FPP: ![]() ChemComp-NH7: ![]() ChemComp-HOH: ![]() ChemComp-ACY: ![]() ChemComp-NH8: |
Source |
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![]() | TRANSFERASE / Prenyltransferase / Metal-binding / Phosphoprotein |