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TitleStructural Basis for the Decarboxylation of Orotidine 5'-Monophosphate (OMP) by Plasmodium Falciparum OMP Decarboxylase
Journal, issue, pagesJ. BIOCHEM. (TOKYO), Vol. 143, Page 69-78, Year 2008
Publish dateSep 26, 2007 (structure data deposition date)
AuthorsTokuoka, K. / Kusakari, Y. / Krungkrai, S.R. / Matsumura, H. / Kai, Y. / Krungkrai, J. / Horii, T. / Inoue, T.
External linksJ. BIOCHEM. (TOKYO) / PubMed:17981823
MethodsX-ray diffraction
Resolution2.65 - 2.7 Å
Structure data

PDB-2za1:
Crystal Structure of orotidine 5'-monophosphate decarboxylase complexed with orotidine 5'-monophosphate from P.falciparum
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-2za2:
Crystal Structure of the apo-form of orotidine-5'-monophosphate decarboxylase from P.falciparum
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2za3:
Crystal Structure of orotidine 5'-monophosphate decarboxylase complexed with uridine 5'-monophosphate from P.falciparum
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-OMP:
OROTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-U5P:
URIDINE-5'-MONOPHOSPHATE

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsLYASE / orotidine 5'-monophosphate decarboxylase / Plasmodium falciparum / orotidine 5'-monophosphate / Pyrimidine biosynthesis / uridine 5'-monophosphate

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