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-Structure paper
Title | Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 4509-4515, Year 2007 |
Publish date | Jun 19, 2007 (structure data deposition date) |
![]() | Wang, Y.F. / Tie, Y. / Boross, P.I. / Tozser, J. / Ghosh, A.K. / Harrison, R.W. / Weber, I.T. |
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Methods | X-ray diffraction |
Resolution | 1.11 - 1.6 Å |
Structure data | ![]() PDB-2qci: ![]() PDB-2qd6: ![]() PDB-2qd7: ![]() PDB-2qd8: ![]() PDB-2z4o: |
Chemicals | ![]() ChemComp-NA: ![]() ChemComp-CL: ![]() ChemComp-ACT: ![]() ChemComp-065: ![]() ChemComp-HOH: ![]() ChemComp-PO4: ![]() ChemComp-DMS: ![]() ChemComp-GOL: |
Source |
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![]() | HYDROLASE / HIV-1 / mutant D30N / protease inhibitor / HIV-1 protease mutant I50V / HIV-1 protease mutant V82A / HIV-1 protease mutant I84V / wild type protease |