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TitleAmorfrutins are Potent Antidiabetic Dietary Natural Products
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 7257-, Year 2012
Publish dateApr 5, 2011 (structure data deposition date)
AuthorsWeidner, C. / De Groot, J.C. / Prasad, A. / Freiwald, A. / Quedenau, C. / Kliem, M. / Witzke, A. / Kodelja, V. / Han, C.-T. / Giegold, S. ...Weidner, C. / De Groot, J.C. / Prasad, A. / Freiwald, A. / Quedenau, C. / Kliem, M. / Witzke, A. / Kodelja, V. / Han, C.-T. / Giegold, S. / Baumann, M. / Klebl, B. / Siems, K. / Mueller-Kuhrt, L. / Schuermann, A. / Schueller, R. / Pfeiffer, A.F.H. / Schroeder, F.C. / Buessow, K. / Sauer, S.
External linksProc. Natl. Acad. Sci. USA / PubMed:22509006
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2yfe:
Ligand binding domain of human PPAR gamma in complex with amorfrutin 1
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-YFE:
Amorfrutin 1

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRECEPTOR / AGONIST / DIABETES / INSULIN RESISTANCE

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