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TitleThe Crystal Structure of Isopenicillin N Synthase with Delta((L)-Alpha-Aminoadipoyl)-(L)-Cysteinyl-(D)-Methionine Reveals Thioether Coordination to Iron.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 516, Page 103-, Year 2011
Publish dateJan 19, 2011 (structure data deposition date)
AuthorsClifton, I.J. / Ge, W. / Adlington, R.M. / Baldwin, J.E. / Rutledge, P.J.
External linksArch. Biochem. Biophys. / PubMed:22001738
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-2y60:
Isopenicillin N synthase with AC-D-methionine
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-M8F:
N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-methionine

ChemComp-FE:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • emericella nidulans (strain fgsc a4 / atcc 38163 / cbs 112.46 / nrrl 194 / m139) (mold)
KeywordsOXIDOREDUCTASE / OXYGENASE / PENICILLIN BIOSYNTHESIS

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