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-Structure paper
Title | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents |
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Journal, issue, pages | Chem. Biol., Vol. 17, Page 1111-, Year 2010 |
Publish date | Jul 29, 2010 (structure data deposition date) |
![]() | Wang, S. / Griffiths, G. / Midgley, C.A. / Barnett, A.L. / Cooper, M. / Grabarek, J. / Ingram, L. / Jackson, W. / Kontopidis, G. / Mcclue, S.J. ...Wang, S. / Griffiths, G. / Midgley, C.A. / Barnett, A.L. / Cooper, M. / Grabarek, J. / Ingram, L. / Jackson, W. / Kontopidis, G. / Mcclue, S.J. / Mcinnes, C. / Mclachlan, J. / Meades, C. / Mezna, M. / Stuart, I. / Thomas, M.P. / Zheleva, D.I. / Lane, D.P. / Jackson, R.C. / Glover, D.M. / Blake, D.G. / Fischer, P.M. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 1.9 Å |
Structure data | ![]() PDB-2xmy: ![]() PDB-2xnb: |
Chemicals | ![]() ChemComp-CDK: ![]() ChemComp-HOH: ![]() ChemComp-Y8L: |
Source |
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![]() | TRANSFERASE / CELL CYCLE / CDK9 INHIBITOR |