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-Structure paper
Title | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. |
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Journal, issue, pages | J. Med. Chem., Vol. 54, Page 580-, Year 2011 |
Publish date | Apr 12, 2010 (structure data deposition date) |
![]() | Caldwell, J.J. / Welsh, E.J. / Matijssen, C. / Anderson, V.E. / Antoni, L. / Boxall, K. / Urban, F. / Hayes, A. / Raynaud, F.I. / Rigoreau, L.J. ...Caldwell, J.J. / Welsh, E.J. / Matijssen, C. / Anderson, V.E. / Antoni, L. / Boxall, K. / Urban, F. / Hayes, A. / Raynaud, F.I. / Rigoreau, L.J. / Raynham, T. / Aherne, G.W. / Pearl, L.H. / Oliver, A.W. / Garrett, M.D. / Collins, I. |
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Methods | X-ray diffraction |
Resolution | 2.3 - 3.4 Å |
Structure data | ![]() PDB-2xbj: ![]() PDB-2xm8: ![]() PDB-2xm9: |
Chemicals | ![]() ChemComp-XBJ: ![]() ChemComp-MG: ![]() ChemComp-NO3: ![]() ChemComp-HOH: ![]() ChemComp-B4W: ![]() ChemComp-LWH: |
Source |
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![]() | TRANSFERASE / DNA REPAIR / PARP / CANCER |