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-Structure paper
Title | Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 132, Page 6827-, Year 2010 |
Publish date | Mar 31, 2010 (structure data deposition date) |
![]() | Binda, C. / Valente, S. / Romanenghi, M. / Pilotto, S. / Cirilli, R. / Karytinos, A. / Ciossani, G. / Botrugno, O.A. / Forneris, F. / Tardugno, M. ...Binda, C. / Valente, S. / Romanenghi, M. / Pilotto, S. / Cirilli, R. / Karytinos, A. / Ciossani, G. / Botrugno, O.A. / Forneris, F. / Tardugno, M. / Edmondson, D.E. / Minucci, S. / Mattevi, A. / Mai, A. |
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Methods | X-ray diffraction |
Resolution | 3.1 - 3.3 Å |
Structure data | ![]() PDB-2xaf: ![]() PDB-2xag: ![]() PDB-2xah: ![]() PDB-2xaj: ![]() PDB-2xaq: ![]() PDB-2xas: |
Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-TCF: ![]() ChemComp-3PL: ![]() ChemComp-TCA: ![]() ChemComp-M84: ![]() ChemComp-M80: |
Source |
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![]() | TRANSCRIPTION / AMINE OXIDASE / CHROMATIN REGULATOR / HISTONE INHIBITOR BINDING / METHYLATION / NUCLEOSOME CORE / OXIDOREDUCTASE / OXIDOREDUCTASE-REPRESSOR COMPLEX / CHROMATIN REMODELLING |