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TitleStructure of Human Serine-Arginine-Rich Protein- Specific Kinase 2 (Srpk2) Bound to Purvalanol B
Journal, issue, pagesTo be Published
Publish dateFeb 26, 2010 (structure data deposition date)
AuthorsPike, A.C.W. / Savitsky, P. / Fedorov, O. / Krojer, T. / Ugochukwu, E. / von Delft, F. / Gileadi, O. / Edwards, A. / Arrowsmith, C.H. / Weigelt, J. ...Pike, A.C.W. / Savitsky, P. / Fedorov, O. / Krojer, T. / Ugochukwu, E. / von Delft, F. / Gileadi, O. / Edwards, A. / Arrowsmith, C.H. / Weigelt, J. / Bountra, C. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-2x7g:
Structure of human serine-arginine-rich protein-specific kinase 2 (SRPK2) bound to purvalanol B
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-PVB:
PURVALANOL B

ChemComp-SO4:
SULFATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SERINE/THREONINE-PROTEIN KINASE / MRNA SPLICING / PHOSPHOPROTEIN / MRNA PROCESSING / DIFFERENTIATION / NUCLEOTIDE-BINDING / SPLICEASOME ASSEMBLY / ATP COMPETITIVE INHIBITOR / KINASE / NUCLEUS / ATP-BINDING / SPLICE FACTOR TRAFFICKING

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