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Structure paper

TitleStructures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 386, Page 666-, Year 2009
Publish dateJun 5, 2009 (structure data deposition date)
AuthorsMitsiki, E. / Papageorgiou, A.C. / Iyer, S. / Thiyagarajan, N. / Prior, S.H. / Sleep, D. / Finnis, C. / Acharya, K.R.
External linksBiochem. Biophys. Res. Commun. / PubMed:19555658
MethodsX-ray diffraction
Resolution2.5 - 2.99 Å
Structure data

PDB-2wk5:
Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

PDB-2wk6:
Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-IUR:
5-IODOURACIL

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / GLYCOSYLTRANSFERASE / DEVELOPMENTAL PROTEIN / ANGIOGENESIS / 5-IODOURACIL / GROWTH FACTOR / ENZYME KINETICS / DIFFERENTIATION / DISEASE MUTATION / THYMIDINE PHOSPHORYLASE / CHEMOTAXIS / MUTAGENESIS / POLYMORPHISM

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