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-Structure paper
Title | Thermodynamic Optimisation in Drug Discovery: A Case Study Using Carbonic Anhydrase Inhibitors. |
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Journal, issue, pages | Chemmedchem, Vol. 4, Page 1985-, Year 2009 |
Publish date | Mar 31, 2009 (structure data deposition date) |
Authors | Scott, A.D. / Phillips, C. / Alex, A. / Flocco, M. / Bent, A. / Randall, A. / O'Brien, R. / Damian, L. / Jones, L.H. |
External links | Chemmedchem / PubMed:19882701 |
Methods | X-ray diffraction |
Resolution | 1.1 - 2.09 Å |
Structure data | PDB-2weg: PDB-2weh: PDB-2wej: PDB-2weo: |
Chemicals | ChemComp-ZN: ChemComp-FBV: ChemComp-GOL: ChemComp-HOH: ChemComp-FB1: ChemComp-FB2: ChemComp-FBW: ChemComp-DMS: |
Source |
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Keywords | LYASE / METAL-BINDING / DISEASE MUTATION / ZINC / CYTOPLASM / ACETYLATION / POLYMORPHISM |