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TitleVersatility of Y-Family Sulfolobus Solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 3563-, Year 2009
Publish dateJan 16, 2009 (structure data deposition date)
AuthorsZhang, H. / Eoff, R.L. / Kozekov, I.D. / Rizzo, C.J. / Egli, M. / Guengerich, F.P.
External linksJ. Biol. Chem. / PubMed:19059910
MethodsX-ray diffraction
Resolution3 - 3.1 Å
Structure data

PDB-2w8k:
Y-family DNA polymerase Dpo4 bypassing N2-naphthyl-guanine adduct in syn orientation
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-2w8l:
Y-family DNA polymerase Dpo4 bypassing N2-naphthyl-guanine adduct in anti orientation
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • sulfolobus solfataricus (archaea)
KeywordsTRANSFERASE/DNA / DNA-DIRECTED DNA POLYMERASE / DNA / DPO4 / ADDUCT / N2-ALKYL / CYTOPLASM / MAGNESIUM / TRANSFERASE / METAL-BINDING / MUTATOR PROTEIN / DNA REPLICATION / NUCLEOTIDYLTRANSFERASE / COMPLEX / POLYMERASE / DNA DAMAGE / DNA REPAIR / DNA-BINDING / TRANSFERASE-DNA complex

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