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Structure paper

TitleCrystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae
Journal, issue, pagesJ. Mol. Biol., Vol. 384, Page 436-, Year 2008
Publish dateJun 13, 2008 (structure data deposition date)
AuthorsXu, G. / Potter, J.A. / Russell, R.J.M. / Oggioni, M.R. / Andrew, P.W. / Taylor, G.L.
External linksJ. Mol. Biol. / PubMed:18835278
MethodsX-ray diffraction
Resolution1.7 - 2.39 Å
Structure data

PDB-2vw0:
Crystal structure of the NanB sialidase from Streptococcus pneumoniae
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2vw1:
Crystal structure of the NanB sialidase from Streptococcus pneumoniae
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

PDB-2vw2:
Crystal structure of the NanB sialidase from Streptococcus pneumoniae
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-DAN:
2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID

ChemComp-NHE:
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / pH buffer*YM

Source
  • streptococcus pneumoniae (bacteria)
KeywordsHYDROLASE / SIALIDASE / GLYCOSIDASE / DRUG DESIGN / NEURAMINIDASE / VIRULENCE FACTOR

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