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-Structure paper
Title | Discovery of Selective Aminothiazole Aurora Kinase Inhibitors |
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Journal, issue, pages | Acs Chem. Biol., Vol. 3, Page 180-, Year 2008 |
Publish date | Nov 15, 2007 (structure data deposition date) |
![]() | Andersen, C.B. / Wan, Y. / Chang, J.W. / Riggs, B. / Lee, C. / Liu, Y. / Sessa, F. / Villa, F. / Kwiatkowski, N. / Suzuki, M. ...Andersen, C.B. / Wan, Y. / Chang, J.W. / Riggs, B. / Lee, C. / Liu, Y. / Sessa, F. / Villa, F. / Kwiatkowski, N. / Suzuki, M. / Nallan, L. / Heald, R. / Musacchio, A. / Gray, N.S. |
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Methods | X-ray diffraction |
Resolution | 1.7 Å |
Structure data | ![]() PDB-2vgp: |
Chemicals | ![]() ChemComp-AD6: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / NUCLEOTIDE-BINDING / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING / COILED COIL / CELL DIVISION / KINASE / CANCER / INCENP / NUCLEUS / MITOSIS / AURORA B / METAL-BINDING / AMINOTHIAZOLE / PHOSPHORYLATION / MAGNESIUM / CELL CYCLE / CENTROMERE / MICROTUBULE |