+Search query
-Structure paper
Title | Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 51, Page 2178-, Year 2008 |
Publish date | Sep 26, 2007 (structure data deposition date) |
Authors | Hohwy, M. / Spadola, L. / Lundquist, B. / Hawtin, P. / Dahmen, J. / Groth-Clausen, I. / Nilsson, E. / Persdotter, S. / Von Wachenfeldt, K. / Folmer, R.H.A. / Edman, K. |
External links | J. Med. Chem. / PubMed:18341273 |
Methods | X-ray diffraction |
Resolution | 1.95 - 2.25 Å |
Structure data | PDB-2vcq: PDB-2vcw: PDB-2vcx: PDB-2vcz: PDB-2vd0: PDB-2vd1: |
Chemicals | ChemComp-GSH: ChemComp-D25: ChemComp-HOH: ChemComp-ZZA: ChemComp-MG: ChemComp-D26: ChemComp-VC3: ChemComp-D27: ChemComp-GOL: ChemComp-D28: |
Source |
|
Keywords | ISOMERASE / PROSTAGLANDIN BIOSYNTHESIS / FATTY ACID BIOSYNTHESIS / PROSTAGLANDIN D2 SYNTHASE / PGDS / ASTHMA / CYTOPLASM / LIPID SYNTHESIS |