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Structure paper

TitleStrictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 130, Page 710-723, Year 2008
Publish dateSep 4, 2007 (structure data deposition date)
AuthorsMaresh, J.J. / Giddings, L.A. / Friedrich, A. / Loris, E.A. / Panjikar, S. / Trout, B.L. / Stockigt, J. / Peters, B. / O'Connor, S.E.
External linksJ. Am. Chem. Soc. / PubMed:18081287
MethodsX-ray diffraction
Resolution3.01 Å
Structure data

PDB-2vaq:
STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH INHIBITOR
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

Chemicals

ChemComp-VAW:
(2S,3R,4S)-methyl 4-(2-(2-(1H-indol-3-yl)ethylamino)ethyl)-2-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-vinyl-3,4-dihydro-2H-pyran-5-carboxylate

ChemComp-HOH:
WATER

Source
  • rauvolfia serpentina (serpentwood)
KeywordsLYASE / ALKALOID METABOLISM / GLYCOPROTEIN / SIX BLADED BETA PROPELLER FOLD / STR1 / SYNTHASE / VACUOLE

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