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-Structure paper
Title | Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid Beta-Glucosidase: Insights Into the Mechanism of Chemical Chaperone Action in Gaucher Disease. |
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Journal, issue, pages | J. Biol. Chem., Vol. 282, Page 29052-, Year 2007 |
Publish date | Jun 17, 2007 (structure data deposition date) |
![]() | Brumshtein, B. / Greenblatt, H.M. / Butters, T.D. / Shaaltiel, Y. / Aviezer, D. / Silman, I. / Futerman, A.H. / Sussman, J.L. |
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Methods | X-ray diffraction |
Resolution | 1.96 - 2 Å |
Structure data | ![]() PDB-2v3d: ![]() PDB-2v3e: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-NBV: ![]() ChemComp-NAG: ![]() ChemComp-HOH: ![]() ChemComp-NND: ![]() ChemComp-PO4: |
Source |
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![]() | HYDROLASE / ACID-BETA-GLUCOSIDASE / N-BUTYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION / SPHINGOLIPID METABOLISM / GAUCHER DISEASE / DISEASE MUTATION / LIPID METABOLISM / POLYMORPHISM / GLYCOPROTEIN / PHARMACEUTICAL / N-BUTYL-DEOXYNOJIRIMYCIN / ALTERNATIVE SPLICING / MEMBRANE / LYSOSOME / GLYCOSIDASE / N-NONYL-DEOXYNOJIRIMYCINALTERNATIVE INITIATION / N-NONYL-DEOXYNOJIRIMYCIN |