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Structure paper

TitleActive Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 102, Page 577-, Year 2005
Publish dateDec 16, 2004 (structure data deposition date)
AuthorsMacheboeuf, P. / Di Guilmi, A.M. / Job, V. / Vernet, T. / Dideberg, O. / Dessen, A.
External linksProc. Natl. Acad. Sci. USA / PubMed:15637155
MethodsX-ray diffraction
Resolution1.9 - 3 Å
Structure data

PDB-2bg1:
Active site restructuring regulates ligand recognition in classA Penicillin-binding proteins (PBPs)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2uwx:
Active site restructuring regulates ligand recognition in class A penicillin-binding proteins
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

PDB-2xd1:
ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CEF:
CEFOTAXIME, C3' cleaved, open, bound form / antibiotic*YM

Source
  • streptococcus pneumoniae (bacteria)
KeywordsPEPTIDOGLYCAN / PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME / CELL WALL / TRANSFERASE / ACYLTRANSFERASE / GLYCOSYLTRANSFERASE / PEPTIDOGLYCAN SYNTHESIS

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