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TitleX-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine.
Journal, issue, pagesBiochemistry, Vol. 38, Page 15174-15184, Year 1999
Publish dateJul 6, 1999 (structure data deposition date)
AuthorsGrishin, N.V. / Osterman, A.L. / Brooks, H.B. / Phillips, M.A. / Goldsmith, E.J.
External linksBiochemistry / PubMed:10563800
MethodsX-ray diffraction
Resolution2 - 2.9 Å
Structure data

PDB-1qu4:
CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-2tod:
ORNITHINE DECARBOXYLASE FROM TRYPANOSOMA BRUCEI K69A MUTANT IN COMPLEX WITH ALPHA-DIFLUOROMETHYLORNITHINE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-DMO:
ALPHA-DIFLUOROMETHYLORNITHINE / medication*YM

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei (eukaryote)
KeywordsLYASE / POLYAMINE METABOLISM / PYRIDOXAL 5'-PHOSPHATE / ALPHA-BETA BARREL

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