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Structure paper

TitleCrystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 36552-36560, Year 2007
Publish dateSep 24, 2007 (structure data deposition date)
AuthorsYou, Z. / Omura, S. / Ikeda, H. / Cane, D.E. / Jogl, G.
External linksJ. Biol. Chem. / PubMed:17942405
MethodsX-ray diffraction
Resolution1.31 - 1.7 Å
Structure data

PDB-2rdn:
Crystal Structure of PtlH with AKG and ent-1PL bound
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-2rdq:
Crystal Structure of PtlH with Fe/alpha ketoglutarate bound
Method: X-RAY DIFFRACTION / Resolution: 1.31 Å

PDB-2rdr:
Crystal Structure of PtlH with Fe/oxalylglycine bound
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2rds:
Crystal Structure of PtlH with Fe/oxalylglycine and ent-1-deoxypentalenic acid bound
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-1PL:
(1S,3aS,5aR,8aS)-1,7,7-trimethyl-1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene-4-carboxylic acid

ChemComp-HOH:
WATER

ChemComp-OGA:
N-OXALYLGLYCINE / inhibitor*YM

Source
  • streptomyces avermitilis (bacteria)
KeywordsOXIDOREDUCTASE / double stranded barrel helix / dioxygenase

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