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-Structure paper
Title | Structure-based optimization of cephalothin-analogue boronic acids as beta-lactamase inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 16, Page 1195-1205, Year 2008 |
Publish date | Sep 20, 2007 (structure data deposition date) |
Authors | Morandi, S. / Morandi, F. / Caselli, E. / Shoichet, B.K. / Prati, F. |
External links | Bioorg. Med. Chem. / PubMed:17997318 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-2rcx: |
Chemicals | ChemComp-SM4: ChemComp-PO4: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / AmpC / beta-lactamase / cephalosporinase / serine hydrolase / Antibiotic resistance / Periplasm |