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-Structure paper
Title | 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 6266-6269, Year 2007 |
Publish date | Aug 27, 2007 (structure data deposition date) |
![]() | Lee, L. / Kreutter, K.D. / Pan, W. / Crysler, C. / Spurlino, J. / Player, M.R. / Tomczuk, B. / Lu, T. |
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Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-2r2m: |
Chemicals | ![]() ChemComp-I50: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / Thrombin / Acute phase / Blood coagulation / Cleavage on pair of basic residues / Disease mutation / Gamma-carboxyglutamic acid / Glycoprotein / Kringle / Protease / Secreted / Serine protease / Zymogen / Protease inhibitor / Serine protease inhibitor / Sulfation / HYDROLASE-HYDROLASE INHIBITOR complex |