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Structure paper

TitlePhenyl- and benzylurea cytokinins as competitive inhibitors of cytokinin oxidase/dehydrogenase: a structural study.
Journal, issue, pagesBiochimie, Vol. 92, Page 1052-1062, Year 2010
Publish dateJul 11, 2007 (structure data deposition date)
AuthorsKopecny, D. / Briozzo, P. / Popelkova, H. / Sebela, M. / Koncitikova, R. / Spichal, L. / Nisler, J. / Madzak, C. / Frebort, I. / Laloue, M. / Houba-Herin, N.
External linksBiochimie / PubMed:20478354
MethodsX-ray diffraction
Resolution1.85 - 2.15 Å
Structure data

PDB-2qkn:
Crystal structure of Maize cytokinin oxidase/dehydrogenase complexed with phenylurea inhibitor CPPU
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-2qpm:
Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with benzylurea inhibitor CPBU
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-3kjm:
Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with phenylurea inhibitor CPPU
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-245:
1-(2-chloropyridin-4-yl)-3-phenylurea

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-246:
1-benzyl-3-(2-chloropyridin-4-yl)urea

Source
  • zea mays (maize)
KeywordsOXIDOREDUCTASE / CYTOKININ OXIDASE/DESHYDROGENASE / FLAVOPROTEIN / FAD / PHENYL-UREA INHIBITOR / OXIDOREDUCTASE/INHIBITOR / CYTOKININ OXIDASE/DEHYDROGENASE / INHIBITOR / Glycoprotein / Secreted / OXIDOREDUCTASE-INHIBITOR complex

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