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Structure paper

TitleCrystal structure of human nicotinamide riboside kinase
Journal, issue, pagesStructure, Vol. 15, Page 1005-1013, Year 2007
Publish dateJun 28, 2007 (structure data deposition date)
AuthorsKhan, J.A. / Xiang, S. / Tong, L.
External linksStructure / PubMed:17698003
MethodsX-ray diffraction
Resolution1.5 - 2.7 Å
Structure data

PDB-2qg6:
Crystal structure of human nicotinamide riboside kinase (NRK1) in complex with nicotinamide mononucleotide (NMN)
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2ql6:
human nicotinamide riboside kinase (NRK1)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-NMN:
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-TIZ:
(1R)-1-[4-(AMINOCARBONYL)-1,3-THIAZOL-2-YL]-1,4-ANHYDRO-D-RIBITOL / inhibitor*YM

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / TRANSFERASE / NRK / nicotinamide riboside kinase / NAD+ / nucleoside monophosphate (NMP) kinase / nicotinamide mononucleotide / ADP / tiazofurin / monophosphate (NMP) kinase

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