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-Structure paper
Title | Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir. |
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Journal, issue, pages | Protein Sci., Vol. 17, Page 1555-1564, Year 2008 |
Publish date | Jul 2, 2007 (structure data deposition date) |
![]() | Saskova, K.G. / Kozisek, M. / Lepsik, M. / Brynda, J. / Rezacova, P. / Vaclavikova, J. / Kagan, R.M. / Machala, L. / Konvalinka, J. |
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Methods | X-ray diffraction |
Resolution | 2.31 - 2.802 Å |
Structure data | ![]() PDB-2qhc: ![]() PDB-2z54: |
Chemicals | ![]() ChemComp-BME: ![]() ChemComp-AB1: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / HIV protease inhibitors; protease-inhibitor structure; Aspartic Protease / Resistant Strain / Complex (Aspartic Protease-Inhibitor) / Aspartic Protease |