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-Structure paper
Title | Evolutionary pathway of HIV resistance analyzed on molecular level: Enzymatic activities, 3-D structures and thermodynamics of HIV proteases resistant to nelfinavir |
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Journal, issue, pages | To be Published |
Publish date | Jun 16, 2007 (structure data deposition date) |
![]() | Kozisek, M. / Bray, J. / Rezacova, P. / Saskova, K. / Rulisek, L. / Brynda, J. / Pokorna, J. / Mammano, F. / Konvalinka, J. |
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Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | ![]() PDB-2qak: |
Chemicals | ![]() ChemComp-1UN: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / HIV protease inhibitors; protease-inhibitor structure; isothermal calorimetry; antiviral resistance development |