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Structure paper

TitleThe crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 22004-22012, Year 2006
Publish dateJun 8, 2007 (structure data deposition date)
AuthorsKavanagh, K.L. / Dunford, J.E. / Bunkoczi, G. / Russell, R.G. / Oppermann, U.
External linksJ. Biol. Chem. / PubMed:16698791
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2q80:
Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GRG:
GERANYLGERANYL DIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / isoprenoid pathway / isopentenyl transferase / Structural Genomics / Structural Genomics Consortium / SGC

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