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TitleDesign of a partial PPARdelta agonist.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 17, Page 4625-4629, Year 2007
Publish dateJun 1, 2007 (structure data deposition date)
AuthorsPettersson, I. / Ebdrup, S. / Havranek, M. / Pihera, P. / Korinek, M. / Mogensen, J.P. / Jeppesen, C.B. / Johansson, E. / Sauerberg, P.
External linksBioorg. Med. Chem. Lett. / PubMed:17560785
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2q5g:
Ligand binding domain of PPAR delta receptor in complex with a partial agonist
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-1FA:
[(7-{[2-(3-MORPHOLIN-4-YLPROP-1-YN-1-YL)-6-{[4-(TRIFLUOROMETHYL)PHENYL]ETHYNYL}PYRIDIN-4-YL]THIO}-2,3-DIHYDRO-1H-INDEN-

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPAR delta

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