+Search query
-Structure paper
Title | The Discovery of Glycine and Related Amino Acid-Based Factor Xa Inhibitors |
---|---|
Journal, issue, pages | BIOORG. MED. CHEM., Vol. 14, Page 4379-4392, Year 2006 |
Publish date | May 24, 2007 (structure data deposition date) |
![]() | Kohrt, J.T. / Filipski, K.J. / Cody, W.L. / Bigge, C.F. / La, F. / Welch, K. / Dahring, T. / Bryant, J.W. / Leonard, D. / Bolton, G. ...Kohrt, J.T. / Filipski, K.J. / Cody, W.L. / Bigge, C.F. / La, F. / Welch, K. / Dahring, T. / Bryant, J.W. / Leonard, D. / Bolton, G. / Narasimhan, L. / Zhang, E. / Peterson, J.T. / Haarer, S. / Sahasrabudhe, V. / Janiczek, N. / Desiraju, S. / Hena, M. / Fiakpui, C. / Saraswat, N. / Sharma, R. / Sun, S. / Maiti, S.N. / Leadley, R. / Edmunds, J.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-2q1j: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-FXI: ![]() ChemComp-HOH: |
Source |
|
![]() | HYDROLASE / COAGULATION FXA / Blood coagulation / Calcium / Cleavage on pair of basic residues / EGF-like domain / Gamma-carboxyglutamic acid / Glycoprotein / Hydroxylation / Polymorphism / Protease / Serine protease / Zymogen |