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-Structure paper
Title | Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants |
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Journal, issue, pages | J. Mol. Biol., Vol. 374, Page 1005-1016, Year 2007 |
Publish date | May 16, 2007 (structure data deposition date) |
Authors | Kozisek, M. / Bray, J. / Rezacova, P. / Saskova, K. / Brynda, J. / Pokorna, J. / Mammano, F. / Rulisek, L. / Konvalinka, J. |
External links | J. Mol. Biol. / PubMed:17977555 |
Methods | X-ray diffraction |
Resolution | 1.85 - 2.5 Å |
Structure data | PDB-2pym: PDB-2pyn: PDB-2q63: PDB-2q64: |
Chemicals | ChemComp-1UN: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / resistance; nelfinavir |