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TitleCrystal structure of the Helicobacter pylori enoyl-acyl carrier protein reductase in complex with hydroxydiphenyl ether compounds, triclosan and diclosan
Journal, issue, pagesProteins, Vol. 69, Page 691-694, Year 2007
Publish dateMar 31, 2007 (structure data deposition date)
AuthorsLee, H.H. / Moon, J.H. / Suh, S.W.
External linksProteins / PubMed:17879346
MethodsX-ray diffraction
Resolution2.3 - 2.5 Å
Structure data

PDB-2pd3:
Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2pd4:
Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-TCL:
TRICLOSAN

ChemComp-HOH:
WATER

ChemComp-DCN:
DICLOSAN

Source
  • helicobacter pylori (bacteria)
KeywordsOXIDOREDUCTASE / antibacterial target / Helicobacter pylori / type II fatty acid biosynthesis / enoyl-ACP-reductase / fabI

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