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TitleCrystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}
Journal, issue, pagesNot Published
Publish dateMar 9, 2007 (structure data deposition date)
AuthorsAdler, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.62 Å
Structure data

PDB-2p3u:
Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-663:
3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / protein inhibitor complex / coagulation cofactor / protease

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