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-Structure paper
Title | Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 3463-3467, Year 2007 |
Publish date | Mar 8, 2007 (structure data deposition date) |
![]() | Alam, M. / Beevers, R.E. / Ceska, T. / Davenport, R.J. / Dickson, K.M. / Fortunato, M. / Gowers, L. / Haughan, A.F. / James, L.A. / Jones, M.W. ...Alam, M. / Beevers, R.E. / Ceska, T. / Davenport, R.J. / Dickson, K.M. / Fortunato, M. / Gowers, L. / Haughan, A.F. / James, L.A. / Jones, M.W. / Kinsella, N. / Lowe, C. / Meissner, J.W. / Nicolas, A.L. / Perry, B.G. / Phillips, D.J. / Pitt, W.R. / Platt, A. / Ratcliffe, A.J. / Sharpe, A. / Tait, L.J. |
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Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | ![]() PDB-2p33: |
Chemicals | ![]() ChemComp-J07: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / JNK3 kinase / inhibitor |