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Structure paper

TitleNon-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 13864-13874, Year 2007
Publish dateFeb 28, 2007 (structure data deposition date)
AuthorsCeccarelli, D.F. / Blasutig, I.M. / Goudreault, M. / Li, Z. / Ruston, J. / Pawson, T. / Sicheri, F.
External linksJ. Biol. Chem. / PubMed:17339315
MethodsX-ray diffraction
Resolution1.811 - 1.91 Å
Structure data

PDB-2p0d:
ArhGAP9 PH domain in complex with Ins(1,4,5)P3
Method: X-RAY DIFFRACTION / Resolution: 1.811 Å

PDB-2p0f:
ArhGAP9 PH domain in complex with Ins(1,3,5)P3
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-2p0h:
ArhGAP9 PH domain in complex with Ins(1,3,4)P3
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-I3P:
D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-I3S:
(1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL

Source
  • homo sapiens (human)
KeywordsLIGAND BINDING PROTEIN / Protein-phosphoinositide complex / Pleckstrin homology domain

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