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-Structure paper
Title | Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 182-185, Year 2007 |
Publish date | Dec 12, 2006 (structure data deposition date) |
![]() | Chappie, T.A. / Humphrey, J.M. / Allen, M.P. / Estep, K.G. / Fox, C.B. / Lebel, L.A. / Liras, S. / Marr, E.S. / Menniti, F.S. / Pandit, J. ...Chappie, T.A. / Humphrey, J.M. / Allen, M.P. / Estep, K.G. / Fox, C.B. / Lebel, L.A. / Liras, S. / Marr, E.S. / Menniti, F.S. / Pandit, J. / Schmidt, C.J. / Tu, M. / Williams, R.D. / Yang, F.V. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2 Å |
Structure data | ![]() PDB-2o8h: ![]() PDB-2ovv: ![]() PDB-2ovy: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-MG: ![]() ChemComp-227: ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() ChemComp-PFH: ![]() ChemComp-PFJ: |
Source |
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![]() | HYDROLASE / phosphodiesterase 10A; Zn-binding site |