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-Structure paper
Title | Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor. |
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Journal, issue, pages | J. Biol. Chem., Vol. 282, Page 23089-23095, Year 2007 |
Publish date | Jan 25, 2007 (structure data deposition date) |
![]() | Crichlow, G.V. / Cheng, K.F. / Dabideen, D. / Ochani, M. / Aljabari, B. / Pavlov, V.A. / Miller, E.J. / Lolis, E. / Al-Abed, Y. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.75 - 1.85 Å |
Structure data | ![]() PDB-2ooh: ![]() PDB-2oow: ![]() PDB-2ooz: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-OX3: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-OX4: ![]() ChemComp-IPA: ![]() ChemComp-OX5: |
Source |
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![]() | ISOMERASE / alternative ligand-binding modes |