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TitleAjulemic Acid, a Synthetic Nonpsychoactive Cannabinoid Acid, Bound to the Ligand Binding Domain of the Human Peroxisome Proliferator-activated Receptor gamma
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 18625-18633, Year 2007
Publish dateJan 21, 2007 (structure data deposition date)
AuthorsAmbrosio, A.L.B. / Dias, S.M.G. / Polikarpov, I. / Zurier, R.B. / Burstein, S.H. / Garratt, R.C.
External linksJ. Biol. Chem. / PubMed:17462987
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2om9:
Ajulemic acid, a synthetic cannabinoid bound to PPAR gamma
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-AJA:
(6AR,10AR)-3-(1,1-DIMETHYLHEPTYL)-1-HYDROXY-6,6-DIMETHYL-6A,7,10,10A-TETRAHYDRO-6H-BENZO[C]CHROMENE-9-CARBOXYLIC ACID / antiinflammatory*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPAR GAMMA / AJULEMIC ACID / CANNABINOID / PARTIAL AGONIST

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