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TitleProbing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 99, Page 1253-1258, Year 2002
Publish dateDec 20, 2006 (structure data deposition date)
AuthorsKoide, A. / Abbatiello, S. / Rothgery, L. / Koide, S.
External linksProc. Natl. Acad. Sci. USA / PubMed:11818562
MethodsX-ray diffraction
Resolution2.95 Å
Structure data

PDB-2ocf:
Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-EST:
ESTRADIOL / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / Estrogen Receptor / LBD / monobody / estradiol / HORMONE-GROWTH FACTOR COMPLEX

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