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TitleCrystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 14, Page 106-113, Year 2007
Publish dateDec 18, 2006 (structure data deposition date)
AuthorsQiu, X. / Mistry, A. / Ammirati, M.J. / Chrunyk, B.A. / Clark, R.W. / Cong, Y. / Culp, J.S. / Danley, D.E. / Freeman, T.B. / Geoghegan, K.F. ...Qiu, X. / Mistry, A. / Ammirati, M.J. / Chrunyk, B.A. / Clark, R.W. / Cong, Y. / Culp, J.S. / Danley, D.E. / Freeman, T.B. / Geoghegan, K.F. / Griffor, M.C. / Hawrylik, S.J. / Hayward, C.M. / Hensley, P. / Hoth, L.R. / Karam, G.A. / Lira, M.E. / Lloyd, D.B. / McGrath, K.M. / Stutzman-Engwall, K.J. / Subashi, A.K. / Subashi, T.A. / Thompson, J.F. / Wang, I.K. / Zhao, H. / Seddon, A.P.
External linksNat. Struct. Mol. Biol. / PubMed:17237796
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2obd:
Crystal Structure of Cholesteryl Ester Transfer Protein
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-2OB:
CHOLESTERYL OLEATE

ChemComp-PCW:
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE / DOPC, phospholipid*YM

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIPID TRANSPORT / cholesteryl ester / lipid transfer protein

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