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Structure paper

TitleCrystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.
Journal, issue, pagesJ. Mol. Biol., Vol. 285, Page 297-309, Year 1999
Publish dateMay 7, 1998 (structure data deposition date)
AuthorsStorici, P. / Capitani, G. / Muller, R. / Schirmer, T. / Jansonius, J.N.
External linksJ. Mol. Biol. / PubMed:9878407
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-2oat:
ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-PFM:
1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAMINOTRANSFERASE / 5-FLUOROMETHYLORNITHINE / PLP-DEPENDENT ENZYME / PYRIDOXAL PHOSPHATE

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