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Structure paper

TitleStructural basis for cofactor-independent dioxygenation in vancomycin biosynthesis.
Journal, issue, pagesNature, Vol. 447, Page 342-345, Year 2007
Publish dateOct 26, 2006 (structure data deposition date)
AuthorsWidboom, P.F. / Fielding, E.N. / Liu, Y. / Bruner, S.D.
External linksNature / PubMed:17507985
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-2np9:
Crystal structure of a dioxygenase in the Crotonase superfamily
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-YE1:
[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE

ChemComp-OXY:
OXYGEN MOLECULE

ChemComp-HOH:
WATER

Source
  • streptomyces toyocaensis (bacteria)
KeywordsOXIDOREDUCTASE / Protein inhibitor complex

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