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TitleHLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Journal, issue, pagesMol. Cell, Vol. 58, Page 1090-1100, Year 2015
Publish dateFeb 18, 2015 (structure data deposition date)
AuthorsKile, A.C. / Chavez, D.A. / Bacal, J. / Eldirany, S. / Korzhnev, D.M. / Bezsonova, I. / Eichman, B.F. / Cimprich, K.A.
External linksMol. Cell / PubMed:26051180
MethodsNMR (solution) / X-ray diffraction
Resolution1.501 Å
Structure data

PDB-2mzn:
NMR structure of the HLTF HIRAN domain in its DNA-bound conformation
Method: SOLUTION NMR

PDB-4s0n:
Crystal Structure of HLTF HIRAN Domain bound to DNA
Method: X-RAY DIFFRACTION / Resolution: 1.501 Å

Chemicals

ChemComp-DT:
THYMIDINE-5'-MONOPHOSPHATE / dTMP*YM

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / HIRAN / HLTF / DNA binding Protein/DNA / alpha+beta / DNA 3'-end binding / DNA binding Protein-DNA complex

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