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TitleA Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes.
Journal, issue, pagesChem. Biol., Vol. 18, Page 531-541, Year 2011
Publish dateJan 3, 2011 (structure data deposition date)
AuthorsBorah, J.C. / Mujtaba, S. / Karakikes, I. / Zeng, L. / Muller, M. / Patel, J. / Moshkina, N. / Morohashi, K. / Zhang, W. / Gerona-Navarro, G. ...Borah, J.C. / Mujtaba, S. / Karakikes, I. / Zeng, L. / Muller, M. / Patel, J. / Moshkina, N. / Morohashi, K. / Zhang, W. / Gerona-Navarro, G. / Hajjar, R.J. / Zhou, M.M.
External linksChem. Biol. / PubMed:21513889
MethodsNMR (solution)
Structure data

PDB-2l84:
Solution NMR structures of CBP bromodomain with small molecule j28
Method: SOLUTION NMR

PDB-2l85:
Solution NMR structures of CBP bromodomain with small molecule of HBS
Method: SOLUTION NMR

Chemicals

ChemComp-J28:
5-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid

ChemComp-L85:
4-[(E)-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / P53

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