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Structure paper

TitleInhibitor-induced structural change in the HCV IRES domain IIa RNA.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 7263-7268, Year 2010
Publish dateFeb 10, 2010 (structure data deposition date)
AuthorsPaulsen, R.B. / Seth, P.P. / Swayze, E.E. / Griffey, R.H. / Skalicky, J.J. / Cheatham, T.E. / Davis, D.R.
External linksProc. Natl. Acad. Sci. USA / PubMed:20360559
MethodsNMR (solution)
Structure data

PDB-2ktz:
Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA
Method: SOLUTION NMR

PDB-2ku0:
Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA
Method: SOLUTION NMR

Chemicals

ChemComp-ISH:
(7R)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine

ChemComp-ISI:
(7S)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine

Source
  • hepatitis c virus
KeywordsRNA / Hepatitis C Virus / RNA Structure / Antiviral

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